Home >> Signaling Pathways >> Apoptosis >> Caspase


Caspases (cysteine-dependent aspartate specific ptotease) are a family of cysteine proteases that play an essential role in cell apoptosis. Caspases contain a conserved QACXG pentapeptide active site motif and are characterized by specificity for aspartic acid in the P1 position. The synthesis of caspases involves the activation of inactive proenzymes, which contain an N-terminal peptide (prodomain) together with two subunits (one small and one large), following cleavage at specific aspartate cleavage sites. Caspases can be classified into three subfamilies, due to phylogenetic analysis, including an ICE subfamily (caspases-1, -4 and -5), a CED-3/CPP32 subfamily (caspases-3, -6, -7, -8, -9 and -10) and an ICH-1/Nedd2 subfamily (caspase-2).

Research Area
Compare Products

  1. Cat.No. Product Name Information
  2. C5524 Ac-DEVD-AFC fluorogenic substrate for activated caspase-3
  3. C5528 Ac-DEVD-CMK cell-permeable, and irreversible inhibitor of caspase
  4. A4418 Ac-IEPD-AFC Recognition motif for serine protease granzyme B
  5. A4419 Ac-LEHD-AFC Fluorogenic caspase substrate
  6. A4016 Apoptosis Activator 2 Indoledione caspase activator, cell-permeable
  7. A1930 Apoptosis Inhibitor Associate with caspase-3 inhibition
  8. A4416 AZ 10417808 Caspase-3 inhibitor,selective non-peptide
  9. A1904 Boc-D-FMK Pan-caspase inhibitor
  10. A9901 Caspase Inhibitor Set I Caspase Inhibitors
  11. A1925 Caspase-3/7 Inhibitor I Caspase-3/7 inhibitor

Items 1 to 10 of 31 total

per page
  1. 1
  2. 2
  3. 3
  4. 4

Set Descending Direction